IpaD of Shigella flexneri Is Independently Required for Regulation of Ipa Protein Secretion and Efficient Insertion of IpaB and IpaC into Host Membranes

Shigella flexneri causes human dysentery after invading the cells of the colonic epithelium. The best-studied effectors of Shigella entry into colonocytes are the invasion plasmid antigens IpaC and IpaB. These proteins are exported via a type III secretion system (TTSS) to form a pore in the host me...

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Détails bibliographiques
Auteurs principaux: Picking, Wendy L., Nishioka, Hiroaki, Hearn, Patricia D., Baxter, M. Aaron, Harrington, Amanda T., Blocker, Ariel, Picking, William D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064949/
https://ncbi.nlm.nih.gov/pubmed/15731041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1432-1440.2005
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