Bile Salts Stimulate Recruitment of IpaB to the Shigella flexneri Surface, Where It Colocalizes with IpaD at the Tip of the Type III Secretion Needle

Shigella flexneri uses its type III secretion apparatus (TTSA) to deliver invasins into human cells. This TTSA possesses an external needle with IpaD at its tip. We now show that deoxycholate promotes the stable recruitment of IpaB to the needle tip without inducing a rapid burst of type III secreti...

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Detalhes bibliográficos
Main Authors: Olive, Andrew J., Kenjale, Roma, Espina, Marianela, Moore, David S., Picking, Wendy L., Picking, William D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865747/
https://ncbi.nlm.nih.gov/pubmed/17296762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01599-06
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