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Activation of Shigella flexneri type 3 secretion requires a host-induced conformational change to the translocon pore

Type 3 secretion systems (T3SSs) are conserved bacterial nanomachines that inject virulence proteins (effectors) into eukaryotic cells during infection. Due to their ability to inject heterologous proteins into human cells, these systems are being developed as therapeutic delivery devices. The T3SS...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Russo, Brian C., Duncan, Jeffrey K., Wiscovitch, Alexandra L., Hachey, Austin C., Goldberg, Marcia B.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879154/
https://ncbi.nlm.nih.gov/pubmed/31725799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007928
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