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Activation of Shigella flexneri type 3 secretion requires a host-induced conformational change to the translocon pore
Type 3 secretion systems (T3SSs) are conserved bacterial nanomachines that inject virulence proteins (effectors) into eukaryotic cells during infection. Due to their ability to inject heterologous proteins into human cells, these systems are being developed as therapeutic delivery devices. The T3SS...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879154/ https://ncbi.nlm.nih.gov/pubmed/31725799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007928 |
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