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Cytoplasmic targeting of IpaC to the bacterial pole directs polar type III secretion in Shigella

Type III secretion (T3S) systems are largely used by pathogenic Gram-negative bacteria to inject multiple effectors into eukaryotic cells. Upon cell contact, these bacterial microinjection devices insert two T3S substrates into host cell membranes, forming a so-called ‘translocon' that is requi...

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Detalhes bibliográficos
Main Authors: Jaumouillé, Valentin, Francetic, Olivera, Sansonetti, Philippe J, Tran Van Nhieu, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234337/
https://ncbi.nlm.nih.gov/pubmed/18188151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601976
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