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Detergent isolation stabilizes and activates the Shigella type III secretion system translocator protein IpaC

Shigella rely on a type III secretion system (T3SS) as the primary virulence factor for invasion and colonization of human hosts. While there are an estimated 90 million Shigella infections, annually responsible for more than 100,000 deaths worldwide, challenges isolating and stabilizing many T3SS p...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Bernard, Abram R., Duarte, Shari M., Kumar, Prashant, Dickenson, Nicholas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921279/
https://ncbi.nlm.nih.gov/pubmed/27297397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.05.015
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