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Detergent isolation stabilizes and activates the Shigella type III secretion system translocator protein IpaC

Shigella rely on a type III secretion system (T3SS) as the primary virulence factor for invasion and colonization of human hosts. While there are an estimated 90 million Shigella infections, annually responsible for more than 100,000 deaths worldwide, challenges isolating and stabilizing many T3SS p...

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Bibliografski detalji
Izdano u:J Pharm Sci
Glavni autori: Bernard, Abram R., Duarte, Shari M., Kumar, Prashant, Dickenson, Nicholas E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921279/
https://ncbi.nlm.nih.gov/pubmed/27297397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2016.05.015
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