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Deoxycholate-Enhanced Shigella Virulence is Regulated by a Rare π-Helix in the Type Three Secretion System Tip Protein IpaD
Type three secretion systems (T3SS) are specialized nano-machines that support infection by injecting bacterial proteins directly into host cells. The Shigella T3SS has uniquely evolved to sense environmental levels of the bile salt deoxycholate (DOC) and upregulate virulence in response to DOC. In...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761661/ https://ncbi.nlm.nih.gov/pubmed/29134812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00836 |
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