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Deoxycholate-Enhanced Shigella Virulence is Regulated by a Rare π-Helix in the Type Three Secretion System Tip Protein IpaD

Type three secretion systems (T3SS) are specialized nano-machines that support infection by injecting bacterial proteins directly into host cells. The Shigella T3SS has uniquely evolved to sense environmental levels of the bile salt deoxycholate (DOC) and upregulate virulence in response to DOC. In...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Bernard, Abram R., Jessop, T. Carson, Kumar, Prashant, Dickenson, Nicholas E.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761661/
https://ncbi.nlm.nih.gov/pubmed/29134812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00836
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