A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer

Receptors tyrosine kinase (RTK) enable normal and tumor cells to perceive and adapt to stimuli present in the microenvironment. These stimuli, also known as growth factors, are important molecular cues actively supporting cancer stem cell (CSC) self-renewal and viability. Since in epithelial ovarian...

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Publicado en:Cell Death Dis
Autores principales: Mazzoldi, Elena Laura, Pavan, Simona, Pilotto, Giorgia, Leone, Kevin, Pagotto, Anna, Frezzini, Simona, Nicoletto, Maria Ornella, Amadori, Alberto, Pastò, Anna
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538673/
https://ncbi.nlm.nih.gov/pubmed/31138788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1656-4
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