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A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer

Receptors tyrosine kinase (RTK) enable normal and tumor cells to perceive and adapt to stimuli present in the microenvironment. These stimuli, also known as growth factors, are important molecular cues actively supporting cancer stem cell (CSC) self-renewal and viability. Since in epithelial ovarian...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Mazzoldi, Elena Laura, Pavan, Simona, Pilotto, Giorgia, Leone, Kevin, Pagotto, Anna, Frezzini, Simona, Nicoletto, Maria Ornella, Amadori, Alberto, Pastò, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538673/
https://ncbi.nlm.nih.gov/pubmed/31138788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1656-4
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