Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

We investigated the metabolic profile of cancer stem cells (CSC) isolated from patients with epithelial ovarian cancer. CSC overexpressed genes associated with glucose uptake, oxidative phosphorylation (OXPHOS), and fatty acid β-oxidation, indicating higher ability to direct pyruvate towards the Kre...

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Detalhes bibliográficos
Main Authors: Pastò, Anna, Bellio, Chiara, Pilotto, Giorgia, Ciminale, Vincenzo, Silic-Benussi, Micol, Guzzo, Giulia, Rasola, Andrea, Frasson, Chiara, Nardo, Giorgia, Zulato, Elisabetta, Nicoletto, Maria Ornella, Manicone, Mariangela, Indraccolo, Stefano, Amadori, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147325/
https://ncbi.nlm.nih.gov/pubmed/24946808
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