Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

We investigated the metabolic profile of cancer stem cells (CSC) isolated from patients with epithelial ovarian cancer. CSC overexpressed genes associated with glucose uptake, oxidative phosphorylation (OXPHOS), and fatty acid β-oxidation, indicating higher ability to direct pyruvate towards the Kre...

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Bibliografski detalji
Glavni autori: Pastò, Anna, Bellio, Chiara, Pilotto, Giorgia, Ciminale, Vincenzo, Silic-Benussi, Micol, Guzzo, Giulia, Rasola, Andrea, Frasson, Chiara, Nardo, Giorgia, Zulato, Elisabetta, Nicoletto, Maria Ornella, Manicone, Mariangela, Indraccolo, Stefano, Amadori, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147325/
https://ncbi.nlm.nih.gov/pubmed/24946808
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