A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer

Receptors tyrosine kinase (RTK) enable normal and tumor cells to perceive and adapt to stimuli present in the microenvironment. These stimuli, also known as growth factors, are important molecular cues actively supporting cancer stem cell (CSC) self-renewal and viability. Since in epithelial ovarian...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Mazzoldi, Elena Laura, Pavan, Simona, Pilotto, Giorgia, Leone, Kevin, Pagotto, Anna, Frezzini, Simona, Nicoletto, Maria Ornella, Amadori, Alberto, Pastò, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538673/
https://ncbi.nlm.nih.gov/pubmed/31138788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1656-4
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