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Aptamer-based Targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cells
AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex liga...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538641/ https://ncbi.nlm.nih.gov/pubmed/31138870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44388-9 |
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