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Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation

G-quadruplexes are a family of four-stranded DNA structures, stabilized by G-quartets, that form in the presence of monovalent cations. Efforts are currently being made to identify ligands that selectively bind to G-quadruplex motifs as these compounds may interfere with the telomere structure, telo...

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Bibliographic Details
Main Authors: Cian, Anne De, Mergny, Jean-Louis
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885647/
https://ncbi.nlm.nih.gov/pubmed/17395639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm098
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