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Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes
Repetitive 5′GGXGG DNA segments abound in, or near, regulatory regions of the genome and may form unusual structures called G-quadruplexes. Using NMR spectroscopy, we demonstrate that a family of 5′GCGGXGGY sequences adopts a folding topology containing double-chain reversals. The topology is compos...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458523/ https://ncbi.nlm.nih.gov/pubmed/16682446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl098 |
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