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The “other” mTOR complex: new insights into mTORC2 immunobiology and their implications

A central role of the mechanistic target of rapamycin (mTOR) in regulation of fundamental cell processes is well-recognized. mTOR functions in two distinct complexes: rapamycin-sensitive mTOR complex (C) 1 and rapamycin-insensitive mTORC2. While the role of mTORC1 in shaping immune responses, includ...

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Bibliografische gegevens
Gepubliceerd in:Am J Transplant
Hoofdauteurs: Dai, Helong, Thomson, Angus W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538441/
https://ncbi.nlm.nih.gov/pubmed/30801921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15320
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