Myelin repair stimulated by CNS-selective thyroid hormone action

Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration and disability. There are currently no approved treatments for MS that stimulate myelin repair. During development, thyroid horm...

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Publicat a:JCI Insight
Autors principals: Hartley, Meredith D., Banerji, Tania, Tagge, Ian J., Kirkemo, Lisa L., Chaudhary, Priya, Calkins, Evan, Galipeau, Danielle, Shokat, Mitra D., DeBell, Margaret J., Van Leuven, Shelby, Miller, Hannah, Marracci, Gail, Pocius, Edvinas, Banerji, Tapasree, Ferrara, Skylar J., Meinig, J. Matthew, Emery, Ben, Bourdette, Dennis, Scanlan, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538346/
https://ncbi.nlm.nih.gov/pubmed/30996143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126329
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