Myelin repair stimulated by CNS-selective thyroid hormone action

Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration and disability. There are currently no approved treatments for MS that stimulate myelin repair. During development, thyroid horm...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hartley, Meredith D., Banerji, Tania, Tagge, Ian J., Kirkemo, Lisa L., Chaudhary, Priya, Calkins, Evan, Galipeau, Danielle, Shokat, Mitra D., DeBell, Margaret J., Van Leuven, Shelby, Miller, Hannah, Marracci, Gail, Pocius, Edvinas, Banerji, Tapasree, Ferrara, Skylar J., Meinig, J. Matthew, Emery, Ben, Bourdette, Dennis, Scanlan, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538346/
https://ncbi.nlm.nih.gov/pubmed/30996143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126329
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