Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein

The interplay among signaling events for endothelial cell (EC) senescence, apoptosis, and activation and how these pathological conditions promote atherosclerosis in the area exposed to disturbed flow (d-flow) in concert remain unclear. The aim of this study was to determine whether telomeric repeat...

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Opis bibliograficzny
Wydane w:JCI Insight
Główni autorzy: Kotla, Sivareddy, Vu, Hang Thi, Ko, Kyung Ae, Wang, Yin, Imanishi, Masaki, Heo, Kyung-Sun, Fujii, Yuka, Thomas, Tamlyn N., Gi, Young Jin, Mazhar, Hira, Paez-Mayorga, Jesus, Shin, Ji-Hyun, Tao, Yunting, Giancursio, Carolyn J., Medina, Jan L.M., Taunton, Jack, Lusis, Aldos J., Cooke, John P., Fujiwara, Keigi, Le, Nhat-Tu, Abe, Jun-ichi
Format: Artigo
Język:Inglês
Wydane: American Society for Clinical Investigation 2019
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538340/
https://ncbi.nlm.nih.gov/pubmed/31045573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124867
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