Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase

BACKGROUND: Disturbed flow (d-flow)–induced senescence and activation of endothelial cells (ECs) have been suggested to have critical roles in promoting atherosclerosis. Telomeric repeat-binding factor 2 (TERF2)-interacting protein (TERF2IP), a member of the shelterin complex at the telomere, regula...

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Udgivet i:Metabolism
Main Authors: Kotla, Sivareddy, Le, Nhat-Tu, Vu, Hang Thi, Ko, Kyung Ae, Gi, Young Jin, Thomas, Tamlyn N., Giancursio, Carolyn, Lusis, Aldos J., Cooke, John P., Fujiwara, Keigi, Abe, Jun-ichi
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059097/
https://ncbi.nlm.nih.gov/pubmed/31476350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2019.153962
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