Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein

The interplay among signaling events for endothelial cell (EC) senescence, apoptosis, and activation and how these pathological conditions promote atherosclerosis in the area exposed to disturbed flow (d-flow) in concert remain unclear. The aim of this study was to determine whether telomeric repeat...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kotla, Sivareddy, Vu, Hang Thi, Ko, Kyung Ae, Wang, Yin, Imanishi, Masaki, Heo, Kyung-Sun, Fujii, Yuka, Thomas, Tamlyn N., Gi, Young Jin, Mazhar, Hira, Paez-Mayorga, Jesus, Shin, Ji-Hyun, Tao, Yunting, Giancursio, Carolyn J., Medina, Jan L.M., Taunton, Jack, Lusis, Aldos J., Cooke, John P., Fujiwara, Keigi, Le, Nhat-Tu, Abe, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538340/
https://ncbi.nlm.nih.gov/pubmed/31045573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124867
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