Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein

The interplay among signaling events for endothelial cell (EC) senescence, apoptosis, and activation and how these pathological conditions promote atherosclerosis in the area exposed to disturbed flow (d-flow) in concert remain unclear. The aim of this study was to determine whether telomeric repeat...

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Опубликовано в: :JCI Insight
Главные авторы: Kotla, Sivareddy, Vu, Hang Thi, Ko, Kyung Ae, Wang, Yin, Imanishi, Masaki, Heo, Kyung-Sun, Fujii, Yuka, Thomas, Tamlyn N., Gi, Young Jin, Mazhar, Hira, Paez-Mayorga, Jesus, Shin, Ji-Hyun, Tao, Yunting, Giancursio, Carolyn J., Medina, Jan L.M., Taunton, Jack, Lusis, Aldos J., Cooke, John P., Fujiwara, Keigi, Le, Nhat-Tu, Abe, Jun-ichi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538340/
https://ncbi.nlm.nih.gov/pubmed/31045573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124867
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