Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation()

Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models. The purpose of this study was to determine whether human gastric adenocarcinomas are similarly dependent on Notch and...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Hibdon, Elise S., Razumilava, Nataliya, Keeley, Theresa M., Wong, Gabriela, Solanki, Sumeet, Shah, Yatrik M., Samuelson, Linda C.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536707/
https://ncbi.nlm.nih.gov/pubmed/31129492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.05.002
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