Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation()

Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models. The purpose of this study was to determine whether human gastric adenocarcinomas are similarly dependent on Notch and...

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Publicat a:Neoplasia
Autors principals: Hibdon, Elise S., Razumilava, Nataliya, Keeley, Theresa M., Wong, Gabriela, Solanki, Sumeet, Shah, Yatrik M., Samuelson, Linda C.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2019
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536707/
https://ncbi.nlm.nih.gov/pubmed/31129492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.05.002
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