Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation()

Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models. The purpose of this study was to determine whether human gastric adenocarcinomas are similarly dependent on Notch and...

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Détails bibliographiques
Publié dans:Neoplasia
Auteurs principaux: Hibdon, Elise S., Razumilava, Nataliya, Keeley, Theresa M., Wong, Gabriela, Solanki, Sumeet, Shah, Yatrik M., Samuelson, Linda C.
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2019
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Original article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536707/
https://ncbi.nlm.nih.gov/pubmed/31129492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.05.002
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