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CRISPR/Cas9 Edited Induced Pluripotent Stem Cell-Based Vascular Tissues to Model Aging and Disease-Dependent Impairment

The discovery of induced pluripotent stem cells (iPSCs) and advancements in genome editing technology introduced a new perspective to disease modeling as genetic factors can now be incorporated to mimic the pathology of interest. Ischemia and age-driven impairment of endothelium is one of the very i...

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Detalhes bibliográficos
Publicado no:Tissue Eng Part A
Main Authors: Acun, Aylin, Zorlutuna, Pinar
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535964/
https://ncbi.nlm.nih.gov/pubmed/30704346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2018.0271
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