Small Molecule Inhibitors of the BfrB–Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

[Image: see text] The iron storage protein bacterioferritin (BfrB) is central to bacterial iron homeostasis. The mobilization of iron from BfrB, which requires binding by a cognate ferredoxin (Bfd), is essential to the regulation of cytosolic iron levels in P. aeruginosa. This paper describes the st...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Punchi Hewage, Achala N. D., Yao, Huili, Nammalwar, Baskar, Gnanasekaran, Krishna Kumar, Lovell, Scott, Bunce, Richard A., Eshelman, Kate, Phaniraj, Sahishna M., Lee, Molly M., Peterson, Blake R., Battaile, Kevin P., Reitz, Allen B., Rivera, Mario
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2019
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535718/
https://ncbi.nlm.nih.gov/pubmed/31038945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b00394
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki