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Inhibiting the BfrB:Bfd Interaction in Pseudomonas aeruginosa Causes Irreversible Iron Accumulation in Bacterioferritin and Iron Deficiency in the Bacterial Cytosol

Iron is an essential nutrient for bacteria but the reactivity of Fe(2+) and the insolubility of Fe(3+) present significant challenges to bacterial cells. Iron storage proteins contribute to ameliorating these challenges by oxidizing Fe(2+) using O(2) and H(2)O(2) as electron acceptors, and by compar...

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Dades bibliogràfiques
Publicat a:Metallomics
Autors principals: Eshelman, Kate, Yao, Huili, Punchi Hewage, Achala N. D., Deay, Jacqueline J., Chandler, Josephine R., Rivera, Mario
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494978/
https://ncbi.nlm.nih.gov/pubmed/28318006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mt00042a
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