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Inhibiting the BfrB:Bfd Interaction in Pseudomonas aeruginosa Causes Irreversible Iron Accumulation in Bacterioferritin and Iron Deficiency in the Bacterial Cytosol
Iron is an essential nutrient for bacteria but the reactivity of Fe(2+) and the insolubility of Fe(3+) present significant challenges to bacterial cells. Iron storage proteins contribute to ameliorating these challenges by oxidizing Fe(2+) using O(2) and H(2)O(2) as electron acceptors, and by compar...
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| Publicado no: | Metallomics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494978/ https://ncbi.nlm.nih.gov/pubmed/28318006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7mt00042a |
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