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Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway

BACKGROUND: Tumor environment has been recognized to affect cancer cell progression, such as tumor-associated macrophages. However, increasing evidences suggest that tumor cells are capable of regulating polarization of tumor-associated macrophages. In this study, we investigate the mechanism of how...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Technol Cancer Res Treat
Hauptverfasser: Lian, Guanghui, Chen, Shuijiao, Ouyang, Miao, Li, Fujun, Chen, Linlin, Yang, Junwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535704/
https://ncbi.nlm.nih.gov/pubmed/31088266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1533033819849068
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