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In Vitro and In Vivo Exposure-Effect Relationship of Liposomal Amphotericin B against Aspergillus fumigatus

In vitro pharmacokinetic/pharmacodynamic data of liposomal amphotericin B (L-AMB) were compared with animal data from neutropenic and nonneutropenic models of azole-susceptible and azole-resistant invasive aspergillosis. L-AMB was equally effective. The in vitro fC(max) (maximum concentration of fre...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Siopi, Maria, Mouton, Johan W., Pournaras, Spyros, Meletiadis, Joseph
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535574/
https://ncbi.nlm.nih.gov/pubmed/30962332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02673-18
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