In Vitro and In Vivo Activities of NS-718, a New Lipid Nanosphere Incorporating Amphotericin B, against Aspergillus fumigatus

We evaluated the in vitro and in vivo potencies of a new lipid nanosphere that incorporates amphotericin B (AmB), NS-718, against Aspergillus fumigatus. The in vitro activity of NS-718 (the MIC at which 90% of strains are inhibited [MIC(90)], 0.25 μg/ml) against 18 isolates of A. fumigatus was simil...

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Main Authors: Otsubo, Takakazu, Maesaki, Shigefumi, Hossain, Mohammad Ashraf, Yamamoto, Yoshihiro, Tomono, Kazunori, Tashiro, Takayoshi, Seki, Junzo, Tomii, Yoshifumi, Sonoke, Satoru, Kohno, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC89146/
https://ncbi.nlm.nih.gov/pubmed/10049253
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