In Vitro and In Vivo Activities of NS-718, a New Lipid Nanosphere Incorporating Amphotericin B, against Aspergillus fumigatus

We evaluated the in vitro and in vivo potencies of a new lipid nanosphere that incorporates amphotericin B (AmB), NS-718, against Aspergillus fumigatus. The in vitro activity of NS-718 (the MIC at which 90% of strains are inhibited [MIC(90)], 0.25 μg/ml) against 18 isolates of A. fumigatus was simil...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Otsubo, Takakazu, Maesaki, Shigefumi, Hossain, Mohammad Ashraf, Yamamoto, Yoshihiro, Tomono, Kazunori, Tashiro, Takayoshi, Seki, Junzo, Tomii, Yoshifumi, Sonoke, Satoru, Kohno, Shigeru
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.471
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