A New Marker of Echinocandin Activity in an In Vitro Pharmacokinetic/Pharmacodynamic Model Correlates with an Animal Model of Aspergillus fumigatus Infection

The lack of a quantifiable marker for echinocandin activity hinders in vitro pharmacokinetic/pharmacodynamic (PK/PD) studies for Aspergillus spp. We developed an in vitro PK/PD model simulating the pharmacokinetics of anidulafungin and assessing its pharmacodynamics against Aspergillus fumigatus wit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Meletiadis, Joseph, Siopi, Maria, Tsakris, Athanassios, Mouton, Johan W., Pournaras, Spyros
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Susceptibility
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923178/
https://ncbi.nlm.nih.gov/pubmed/29463527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02322-17
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg