An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy

An engineered oncolytic herpes virus shows enhanced intratumoral spread, resistance to NK cell clearance and improved efficacy against brain cancer in mice.

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Detaylı Bibliyografya
Yayımlandı:Nat Biotechnol
Asıl Yazarlar: Xu, Bo, Ma, Rui, Russell, Luke, Yoo, Ji Young, Han, Jianfeng, Cui, Hanwei, Yi, Ping, Zhang, Jianying, Nakashima, Hiroshi, Dai, Hongsheng, Chiocca, E. Antonio, Kaur, Balveen, Caligiuri, Michael A, Yu, Jianhua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535376/
https://ncbi.nlm.nih.gov/pubmed/30475349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4302
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