Role of Cysteine-rich 61 Protein (CCN1) in Macrophage-mediated Oncolytic Herpes Simplex Virus Clearance

Glioblastoma is a devastating disease, and there is an urgent need to develop novel therapies, such as oncolytic HSV1 (OV) to effectively target tumor cells. OV therapy depends on tumor-specific replication leading to destruction of neoplastic tissues. Host responses that curtail virus replication l...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Thorne, Amy Haseley, Meisen, Walter H, Russell, Luke, Yoo, Ji Young, Bolyard, Chelsea M, Lathia, Justin D, Rich, Jeremy, Puduvalli, Vinay K, Mao, Hsiaoyin, Yu, Jianhua, Caligiuri, Michael A, Tridandapani, Susheela, Kaur, Balveen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435480/
https://ncbi.nlm.nih.gov/pubmed/24895995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.101
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