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PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance
Engineered oncolytic viruses are used clinically to destroy cancer cells and have the ability to boost anticancer immunity. Phosphatase and tensin homolog deleted on chromosome 10 loss is common across a broad range of malignancies, and is implicated in immune escape. The N-terminally extended isofo...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258708/ https://ncbi.nlm.nih.gov/pubmed/30479334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07344-1 |
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