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Adenovirus-mediated ABCC6 Gene Therapy for Heritable Ectopic Mineralization Disorders
Loss-of-function mutations in the ABCC6 gene cause pseudoxanthoma elasticum (PXE) and type 2 generalized arterial calcification of infancy (GACI), heritable ectopic mineralization disorders without effective treatment. ABCC6 encodes the putative efflux transporter ABCC6 which is predominantly expres...
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| Publicado no: | J Invest Dermatol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535136/ https://ncbi.nlm.nih.gov/pubmed/30639429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.12.017 |
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