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Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

During skeletal muscle regeneration, muscle stem cells (MuSCs) respond to multiple signaling inputs that converge onto mammalian target of rapamycin complex 1 (mTORC1) signaling pathways. mTOR function is essential for establishment of the differentiation-committed progenitors (early stage of differ...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kikani, Chintan K., Wu, Xiaoying, Fogarty, Sarah, Kang, Seong Anthony Woo, Dephoure, Noah, Gygi, Steven P., Sabatini, David M., Rutter, Jared
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534978/
https://ncbi.nlm.nih.gov/pubmed/31072927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804013116
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