Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis

PAS domain containing protein kinase (Pask) is an evolutionarily conserved protein kinase implicated in energy homeostasis and metabolic regulation across eukaryotic species. We now describe an unexpected role of Pask in promoting the differentiation of myogenic progenitor cells, embryonic stem cell...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Kikani, Chintan K, Wu, Xiaoying, Paul, Litty, Sabic, Hana, Shen, Zuolian, Shakya, Arvind, Keefe, Alexandra, Villanueva, Claudio, Kardon, Gabrielle, Graves, Barbara, Tantin, Dean, Rutter, Jared
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2016
Teme:
Biochemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035144/
https://ncbi.nlm.nih.gov/pubmed/27661449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17985
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