Structural Bases of PAS Domain-regulated Kinase (PASK) Activation in the Absence of Activation Loop Phosphorylation

Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) is an evolutionary conserved protein kinase that coordinates cellular metabolism with metabolic demand in yeast and mammals. The molecular mechanisms underlying PASK regulation, however, remain unknown. Herein, we describe a crystal structur...

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Bibliografski detalji
Glavni autori: Kikani, Chintan K., Antonysamy, Stephen A., Bonanno, Jeffrey B., Romero, Rich, Zhang, Feiyu Fred, Russell, Marijane, Gheyi, Tarun, Iizuka, Miyo, Emtage, Spencer, Sauder, J. Michael, Turk, Benjamin E., Burley, Stephen K., Rutter, Jared
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003402/
https://ncbi.nlm.nih.gov/pubmed/20943661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157594
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