Human Mutation within Per-Arnt-Sim (PAS) Domain-containing Protein Kinase (PASK) Causes Basal Insulin Hypersecretion

PAS kinase (PASK) is a glucose-regulated protein kinase involved in the control of pancreatic islet hormone release and insulin sensitivity. We aimed here to identify mutations in the PASK gene that may be associated with young-onset diabetes in humans. We screened 18 diabetic probands with unelucid...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Semplici, Francesca, Vaxillaire, Martine, Fogarty, Sarah, Semache, Meriem, Bonnefond, Amélie, Fontés, Ghislaine, Philippe, Julien, Meur, Gargi, Diraison, Frederique, Sessions, Richard B., Rutter, Jared, Poitout, Vincent, Froguel, Philippe, Rutter, Guy A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243507/
https://ncbi.nlm.nih.gov/pubmed/22065581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254995
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker