Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis

PAS domain containing protein kinase (Pask) is an evolutionarily conserved protein kinase implicated in energy homeostasis and metabolic regulation across eukaryotic species. We now describe an unexpected role of Pask in promoting the differentiation of myogenic progenitor cells, embryonic stem cell...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Kikani, Chintan K, Wu, Xiaoying, Paul, Litty, Sabic, Hana, Shen, Zuolian, Shakya, Arvind, Keefe, Alexandra, Villanueva, Claudio, Kardon, Gabrielle, Graves, Barbara, Tantin, Dean, Rutter, Jared
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2016
Onderwerpen:
Biochemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035144/
https://ncbi.nlm.nih.gov/pubmed/27661449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17985
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