Concomitant KRAS and BRAF mutations in colorectal cancer

BRAF and KRAS are two key oncogenes in the RAS/RAF/MEK/MAP-kinase signaling pathway. While previously considered mutually exclusive, concomitant mutations in both KRAS and BRAF genes have been identified in colorectal cancer (CRC). The clinical outcome of these patients remains undetermined. We pres...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Gastrointest Oncol
Hauptverfasser: Midthun, Lauren, Shaheen, Shagufta, Deisch, Jeremy, Senthil, Maheswari, Tsai, James, Hsueh, Chung-Tsen
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2019
Schlagworte:
Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534722/
https://ncbi.nlm.nih.gov/pubmed/31183211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2019.01.10
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge