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Concomitant KRAS and BRAF mutations in colorectal cancer
BRAF and KRAS are two key oncogenes in the RAS/RAF/MEK/MAP-kinase signaling pathway. While previously considered mutually exclusive, concomitant mutations in both KRAS and BRAF genes have been identified in colorectal cancer (CRC). The clinical outcome of these patients remains undetermined. We pres...
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| Publicat a: | J Gastrointest Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
AME Publishing Company
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534722/ https://ncbi.nlm.nih.gov/pubmed/31183211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2019.01.10 |
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