Concomitant KRAS and BRAF mutations in colorectal cancer

BRAF and KRAS are two key oncogenes in the RAS/RAF/MEK/MAP-kinase signaling pathway. While previously considered mutually exclusive, concomitant mutations in both KRAS and BRAF genes have been identified in colorectal cancer (CRC). The clinical outcome of these patients remains undetermined. We pres...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Gastrointest Oncol
Main Authors: Midthun, Lauren, Shaheen, Shagufta, Deisch, Jeremy, Senthil, Maheswari, Tsai, James, Hsueh, Chung-Tsen
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2019
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534722/
https://ncbi.nlm.nih.gov/pubmed/31183211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2019.01.10
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker