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Mutant Isocitrate Dehydrogenase Inhibitors as Targeted Cancer Therapeutics
The identification of heterozygous neomorphic isocitrate dehydrogenase (IDH) mutations across multiple cancer types including both solid and hematologic malignancies has revolutionized our understanding of oncogenesis in these malignancies and the potential for targeted therapeutics using small mole...
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| Gepubliceerd in: | Front Oncol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6534082/ https://ncbi.nlm.nih.gov/pubmed/31165048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00417 |
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