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Xanthatin inhibits STAT3 and NF‐κB signalling by covalently binding to JAK and IKK kinases

Aberrant activation of the signal transducer and activator of transcription 3 (STAT3) and the nuclear factor‐κB (NF‐κB) signalling pathways is associated with the development of cancer and inflammatory diseases. JAKs and IKKs are the key regulators in the STAT3 and NF‐κB signalling respectively. The...

詳細記述

保存先:
書誌詳細
出版年:J Cell Mol Med
主要な著者: Liu, Man, Xiao, Cheng‐qian, Sun, Ming‐wei, Tan, Min‐jia, Hu, Li‐hong, Yu, Qiang
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533482/
https://ncbi.nlm.nih.gov/pubmed/30993883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14322
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