Cytokine Production In Myelofibrosis Exhibits Differential Responsiveness To JAK-STAT, MAP Kinase, And NFκB Signaling

The distinct clinical features of myelofibrosis (MF) have been attributed in part to dysregulated inflammatory cytokine production. Circulating cytokine levels are elevated in MF patients; a subset of which have been shown to be poor prognostic indicators. In this study, cytokine overproduction was...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Fisher, Daniel A.C., Miner, Cathrine A., Engle, Elizabeth K., Hu, Hengrui, Collins, Taylor B., Zhou, Amy, Allen, Maggie J., Malkova, Olga, Oh, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813809/
https://ncbi.nlm.nih.gov/pubmed/30718771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0379-y
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