Mass Cytometry Analysis Reveals Hyperactive NF Kappa B Signaling in Myelofibrosis and Secondary Acute Myeloid Leukemia

Myeloproliferative neoplasms (MPNs) feature a malignant clone containing the JAK2 V617F mutation, or another mutation causing dysregulated JAK2 kinase activity. The multiple disease phenotypes of MPNs, and their tendency to transform phenotypically, suggest pathophysiologic heterogeneities beyond a...

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Publicado no:Leukemia
Main Authors: Fisher, Daniel A.C., Malkova, Olga, Engle, Elizabeth K., Miner, Cathrine, Fulbright, Mary C., Behbehani, Gregory K., Collins, Taylor B., Bandyopadhyay, Shovik, Zhou, Amy, Nolan, Garry P., Oh, Stephen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540814/
https://ncbi.nlm.nih.gov/pubmed/28008177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.377
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