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Mapping connections in signaling networks with ambiguous modularity

Modular Response Analysis (MRA) is a suite of methods that under certain assumptions permits the precise reconstruction of both the directions and strengths of connections between network modules from network responses to perturbations. Standard MRA assumes that modules are insulated, thereby neglec...

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Détails bibliographiques
Publié dans:NPJ Syst Biol Appl
Auteurs principaux: Lill, Daniel, Rukhlenko, Oleksii S., Mc Elwee, Anthony James, Kashdan, Eugene, Timmer, Jens, Kholodenko, Boris N.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533310/
https://ncbi.nlm.nih.gov/pubmed/31149348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-019-0096-1
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