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New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling
RAS is the most frequently mutated gene across human cancers, but developing inhibitors of mutant RAS has proven to be challenging. Given the difficulties of targeting RAS directly, drugs that impact the other components of pathways where mutant RAS operates may potentially be effective. However, th...
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| Udgivet i: | Semin Cancer Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123307/ https://ncbi.nlm.nih.gov/pubmed/29518522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.02.008 |
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