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New insights into RAS biology reinvigorate interest in mathematical modeling of RAS signaling

RAS is the most frequently mutated gene across human cancers, but developing inhibitors of mutant RAS has proven to be challenging. Given the difficulties of targeting RAS directly, drugs that impact the other components of pathways where mutant RAS operates may potentially be effective. However, th...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Semin Cancer Biol
Egile Nagusiak: Erickson, Keesha E., Rukhlenko, Oleksii S., Posner, Richard G., Hlavacek, William S., Kholodenko, Boris N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123307/
https://ncbi.nlm.nih.gov/pubmed/29518522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.02.008
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