Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor

Receptor tyrosine kinases (RTKs) typically contain multiple autophosphorylation sites in their cytoplasmic domains. Once activated, these autophosphorylation sites can recruit downstream signaling proteins containing Src homology 2 (SH2) and phosphotyrosine-binding (PTB) domains, which recognize pho...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS Comput Biol
Hlavní autoři: Erickson, Keesha E., Rukhlenko, Oleksii S., Shahinuzzaman, Md, Slavkova, Kalina P., Lin, Yen Ting, Suderman, Ryan, Stites, Edward C., Anghel, Marian, Posner, Richard G., Barua, Dipak, Kholodenko, Boris N., Hlavacek, William S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353226/
https://ncbi.nlm.nih.gov/pubmed/30653502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006706
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky